Flow simulations of an air distribution system have been carried out using the CFD code FLUENT/UNS . The purpose of this study is to validate this complex flow problem versus experimental data. Two modes of the climate system are investigated; the Ventilation mode and the Floor/Defroster mode. The complete geometrical model contains all ducts, central unit, heat exchangers, defroster and nozzles of the air distribution system. A high level of geometrical detailing in the mesh, consisting of 2.1 - 3.3 million cells, is used. The study shows that CFD has a potential to give reliable results, even for complex systems, like air distribution systems, if used in a controlled manner.