In this paper an algorithm is developed for combining finite element analysis and boundary element techniques in order to compute the noise radiated from a panel subjected to boundary layer loading. The excitation is presented in terms of the auto and cross power spectral densities of the fluctuating wall pressure. The structural finite element model for the panel is divided into a number of sub-panels. A uniform fluctuating pressure is applied as excitation on each sub-panel separately. The corresponding vibration is computed, and is utilized as excitation for an acoustic boundary element analysis. The acoustic response is computed at any data recovery point of interest. The relationships between the acoustic response and the pressure excitation applied at each particular sub-panel constitute a set of transfer functions. They are combined with the spectral densities of the excitation for computing the noise generated from the vibration of the panel subjected to the boundary layer excitation. The development presented in this paper has the potential of computing wind noise in automotive applications, or boundary layer noise in aircraft applications.