Bioluminescent Bioreporter Integrated Circuits (BBICs): Whole-Cell Environmental Monitoring Devices 1

Paper #:
  • 1999-01-2152

Published:
  • 1999-07-12
Citation:
Simpson, M., Paulus, M., Jellison, G., Sayler, G. et al., "Bioluminescent Bioreporter Integrated Circuits (BBICs): Whole-Cell Environmental Monitoring Devices1," SAE Technical Paper 1999-01-2152, 1999, https://doi.org/10.4271/1999-01-2152.
Pages:
7
Abstract:
We report a chemical sensing technology composed of engineered bioluminescent bacteria placed on an integrated microluminometer. The bacteria have been engineered to luminesce when the targeted compound is metabolized, while the microluminometer detects, processes, and then reports the magnitude of this optical signal. In this work we report our progress in the development of these biosensors and present data from our early prototypes.
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