The Rotating Disk Analytical System (R-DAS) is an in-situ, bio-analytical technology, which utilizes a micro-fluidic disk with similar form factor as an audio compact disc to enhance and augment microgravity-based cellular and molecular biology research. The current micro-fluidic assay performs live cell/dead cell analysis using fluorescent microscopy. Image acquisition and analysis are performed for each of the selected microscope slide windows. All images are stored for later download and possible further post analysis. The flight version of the R-DAS will occupy a double mid-deck shuttle locker or one quarter of an ISS rack.The control system for the R-DAS consists of a set of interactive software components. These components interact with one another to control disk rotation, vertical and horizontal stage motion, sample incubation, image acquisition and analysis, and human interface. The control architecture is open and reconfigurable, allowing rapid integration of future biological protocols, each with new, unique mixing, incubation, and imaging requirements.