This paper reviews the state of the art on analytical design of cockpit modules in two most crucial performance categories: safety and comfort. On safety, applications of finite element analysis (FEA) for achieving robust designs that meet FMVSS 201, 208 and 214 requirements and score top frontal and side NCAP star-ratings are presented. On comfort, focus is placed on Noise, Vibration and Harshness (NVH) performance. Cutting-edge analytical tools for Buzz, Squeak and Rattle (BSR) avoidance and passenger compartment noise reduction are demonstrated. Most of the analytical results shown in this paper are based on the development work of a real-life application program. Correlations between the analytical results and physical test results are included. Examples of Computational Fluid Dynamics (CFD) analysis for climate control are also included. At the end, the road map toward 100 percent virtual prototyping and validation is presented.