The fatigue behavior of Hilok fastener joints under constant amplitude loading has been investigated experimentally. The effects of load transfer in an unbalanced joint configuration was characterized in terms of a stress severity factor relative to the open-hole configuration. The experimental data indicates that the clamp-up forces dominate the performance of fastener joints with the open-hole fatigue life being the lower bound at the stress levels investigated. The failure modes were observed to transition from a net-section type failure across the minimum section to a fretting induced failure at some distance from the hole. The experimental data has been used to develop stress severity factors to be used as a measure of the fatigue quality of the fastener joints.