Optimization methodology employing CFD for the aerodynamic design of automotive car styling is presented. The optimization process consists of three stages: Design of Experiments (DOE), Response Surface Modeling (RSM), and optimization algorithm execution. RSM requires a number of CFD calculations in order to ensure its accuracy, making it difficult to apply the RSM to aerodynamic design optimization. In order to resolve this issue, Adaptive Multi Stage RSM (AMS-RSM) was conceived. This method provided the response surface its required accuracy and robustness. The optimization process was realized by constructing an automatic optimization system consisting of software.