There is a growing interest in using pressure sensors to sense side impacts, where the pressure change inside the door cavity is monitored and used to discriminate trigger and non-trigger incidents. In this paper, a pressure sensor simulation capability for side impact sensing calibration is presented. The ability to use simulations for side impact sensing calibration early in the vehicle program development process could reduce vehicle development cost and time. It could also help in evaluating sensor locations by studying the effects of targeted impact points and contents in the door cavity. There are two modeling methods available in LS-DYNA for predicting pressure change inside a cavity, namely airbag method and fluid structure interaction method. A suite of side impact calibration events of a study vehicle were simulated using these two methods. The simulated door cavity pressure time histories were then extracted to calibrate the side sensing system of the study vehicle. The calibration result shows that both the airbag method and the fluid structure interaction method are capable of predicting the pressure change inside the door cavity for side impact sensing calibration purposes, albeit the former requires much less computer run time than the latter.