Very large multi-axis CNC machines offer a special challenge for efficient and accurate machine compensation. Aerospace applications demand tight tolerances, but conventional compensation methods become expensive for large machines. Volumetric compensation offers an approach for reducing costs and improving accuracies. A unique control architecture enabled by volumetric compensation enables the use of a single part program by multiple machines. Combining multiple technologies (a proprietary volumetric compensation solver program, Spatial Analyzer, API's Active Target, a laser tracker and bespoke CNC-Tracker communication software for measurement triggering) significantly reduces machine compensation time. Available analysis tools also enable the engineer to evaluate measurement uncertainties and determine the best locations for additional stations as well as quantify the accuracy benefits such stations would offer.