Diesel Particulate Filter (DPF) system is considered as the most effective method to reduce particulate mater (PM) out of diesel exhaust. In general, silicon carbide (SiC) has been employed as the base materials for DPF substrate in diesel vehicles. Currently, a material, called cordierite (Cd), has been adopted for the DPF in a modern SUV with 2-liter CRDI diesel engine, complying EURO-5 emission regulation. Instead of its lower cost, Cd-based substrate was disadvantageous on thermal conductivity and heat capacity relative to SiC. In this work, the problems (i.e., face crack), initiated by the thermal drawbacks, were investigated as it applied into the DPF substrate. As the countermeasures to overcome, a control optimization of regeneration temperature elevation and an introduction of ingenious multiple regeneration strategy at problematic conditions were proposed and verified through real-road endurance tests.