The recent increase in oil prices and environmental concerns have attracted various research efforts on hybrid electric vehicles (HEVs) which provide promising alternatives to conventional engine-powered vehicles with better fuel economy and fewer emissions. To speed up the design and prototyping processes of new HEVs, a method that automatically generates mathematics equations governing the vehicle system response in an optimized symbolic form is desirable. To achieve this goal, we employed MapleSimTM, a new physical modeling tool developed by Maplesoft Inc., to develop the multi-domain model of a series-HEV, utilizing the symbolic computing algorithms of Maple software package to generate an optimized set of governing equations. The HEV model consists of a mean-value internal combustion engine (ICE), a chemistry-based Ni-MH battery pack, and a multibody vehicle model. Simulations are then used to demonstrate the performance of the developed HEV system. Simulation results show that the model is viable and the number of governing equations is reduced significantly, resulting in a computationally efficient system.