The main purpose of the lubrication in the rolling bearing is to avoid and to reduce the metal to metal contact, thus it is possible to reduce the friction and to prevent the wear between the balls and the raceways. Consequently, the rolling bearing should work with grease or oil inside to guarantee an oil film between the balls and the raceways, thus this grease should stay inside the bearing. To avoid the grease loss the bearing normally may have a sealing but even so a little grease loss can occur. Hence the present investigation was initiated because of the need to understand a grease loss and the basic parameter that has influence on this. To help the elaboration of the experimental tests was used a DOE technique, thus it was possible to determinate simultaneously the individual and interactive effects of many factors that affect in the grease loss. The results were satisfactory and it was able to visualize the operating parameters that have a higher influence in the grease leak and also the behavior of the grease leak in a period of time.