In an automotive air-conditioning (AC) system, the amount of work done by the compressor is also influenced by the suction line which meters the refrigerant flow. Optimizing the AC suction line routing has thus become an important challenge and the plumbing designers are required to come up with innovative packaging solutions. These solutions are required in the early design stages when prototypes are not yet appropriate. In such scenarios, one-dimensional (1D) simulations shall be employed to compute the pressure drop for faster and economical solution. In this paper, an approach of creating a modeling tool for suction line pressure drop prediction is discussed. Using DFSS approach L12 design iterations are created and simulations are carried out using 1D AMESim software. Prototypes are manufactured and tested on HVAC bench calorimeter. AC suction line pressure drop predicted using the 1D modeling co-related well with the test data and the error is less than 5%.