To comply with the new regulations on particulate matter emissions, the manufacturers of light-duty as well as heavy-duty vehicles more commonly use diesel particulate filters (DPF). The regeneration of DPF depends to a significant extent on the properties of the soot stored.Within the Cluster of Excellence "Tailor-Made Fuels from Biomass (TMFB)" at RWTH Aachen University, the Institute for Combustion Engines carried out a detailed investigation program to explore the potential of future biofuel candidates for optimized combustion systems. The experiments for particulate measurements and analysis were conducted on a EURO 6-compliant High Efficiency Diesel Combustion System (HECS) with petroleum-based diesel fuel as reference and a today's commercial biofuel (i.e., FAME) as well as a potential future biomass-derived fuel candidate (i.e., 2-MTHF/DBE).Thermo gravimetric analyzer (TGA) was used in this study to evaluate the oxidative reactivity of the soot. A "Laboratory Gas Test Bench (LGB)" was used to determine the kinetics of soot oxidation mechanism considering impact of soot properties on its burning behavior inside a DPF. The kinetics of soot oxidation with O₂ was studied as well as the oxidation with NO₂ in order to cover thermal filter regeneration as well as CRT® regeneration.Experimental results from LGB and TGA suggest that the soot from future biomass-derived fuel candidate has lower activation energy, thereby; lower oxidation temperatures compared to petroleum-based diesel fuel.