In recent years, interest in microperforated panels (MPPs) has been growing in the automotive industry and elsewhere. Acoustic performance prediction is an important step toward understanding and designing MPPs. This paper outlines a start-to-finish procedure to predict the transfer impedance of a particular MPP based on its hole geometry and to further use this information in a simple plane wave application. A computational fluid dynamics (CFD) approach was used to calculate the impedance of the MPP and the results compared to impedance tube and flow resistance measurements. The transfer impedance results were then used to create a computationally efficient acoustic finite element (FE) model. The results of the acoustic FE model were also compared to impedance tube measurements.