The purpose of this study is to analyze the piston skirt friction reduction effect of a diamond-like carbon (DLC)-coated wrist pin. The floating liner method and elasto-hydrodynamic lubrication (EHL) simulation were used to analyze piston skirt friction. The experimental results showed that a DLC-coated wrist pin reduced cylinder liner friction, and that this reduction was particularly large at low engine speeds and large pin offset conditions. Friction was particularly reduced at around the top and bottom dead center positions (TDC and BDC). EHL simulation confirmed that a DLC-coated wrist pin affects the piston motion and reduces the contact pressure between the piston skirt and cylinder liner.