A combined Computer Aided Engineering (CAE) simulation and physical fatigue testing of a passenger car exhaust system resonator with wire mesh seal between the inlet and outlet pipe is performed to evaluate the durability and improvise the design. The outlet pipe end cap of the exhaust system resonator deformed and cracked at the fillet region repeatedly upon the application of the maximum load from a pre developed accelerated specification test. However, the system meets the end usage on-road durability target of 5 years / 1,00,000 km. There is a gap between the accelerated bench test and the end usage durability target. The current study correlates CAE simulation and biaxial fatigue testing and improvise possible alternate resonator design. Conventionally, components passing the accelerated test always meets the end usage durability target whereas components meeting the end usage durability target need not necessarily pass the accelerated test. Developing accelerated test procedure from Road Load Data Acquisation (RLDA) on an application specific vehicle is the way to bridge the gap between end usage durability target and accelerated test.