Vehicle systems often operate with some degree of uncertainty. This study applies the Chebyshev interval method to model vehicle dynamic systems operating in the presence of interval parameters. A full vehicle model is used as the numerical model and the methodology is illustrated on the steering wheel angle pulse input test. In the numerical simulation, suspension stiffness coefficients and suspension damping coefficients are chosen as interval parameters and lateral acceleration and yaw rate are chosen to capture vehicle dynamic characteristics. System responses in time domain are validated against Monte Carlo simulations and against the scanning approach. Results indicate that the Chebyshev interval method is more efficient than Monte Carlo simulations. The results of scanning method are similar to the ones obtained with the Chebyshev interval method. The overall conclusion is that the Chebyshev interval method is a powerful approach for the simulation of multibody dynamic systems with interval parameters.