Design work for truck suspension systems requires multi-objective optimization using a large number of parameters that cannot be solved in a simple way. This paper proposes a process-based systematization concept for ride comfort design using a set-based design method. A truck was modeled with a minimum of 13 degrees of freedom, and suspension performance under various vehicle speeds, road surface conditions, and load amounts was calculated. The range of design parameters for the suspension, the range of performance requirements, and the optimal values within these ranges were defined based on the knowledge and know-how of experienced design engineers. The final design of the suspension was installed in a prototype truck and evaluated. The performance of the truck satisfied all the objectives and the effectiveness of the set-based design approach was confirmed.