A new electric powertrain and axle for light/medium trucks is presented. The indoor testing and the simulation of the dynamic behavior are performed. The powertrain and axle has been produced by Streparava and tested at the Laboratory for the Safety of Transport of the Politecnico di Milano. The tests were aimed at defining the multi-physics perfomance of the powertrain and axle (efficiency, acceleration and braking, temperature and NVH).The whole system for indoor tests was composed by the powertrain and axle (electric motor, driveline, suspensions, wheels) and by the test rig (drums, driveline and electric motor). The (driving) axle was positioned on a couple of drums, and the drums provided the proper torques to the wheels to reproduce acceleration and braking. Additionally a cleat fixed on one drum excited the vibration of the suspensions and allowed assessing NVH performance.The simulations were based on a special co-simulation between 1D-AMESIM and VIRTUAL.LAB. The contact between the wheels and the drums of the test rig were simulated by means of VIRTUAL.LAB. The simulation of the whole system was performed quickly. The comparison between the simulations and the experiments is satisfactory.The indoor test facility allows the quick tuning of the powertrain and axle parameters to meet the technical specification related to a particular application.