In the context of evolving market conditions the Three-Way Catalyst (TWC) is entering an exciting new phase. It remains the main emission control strategy for gasoline powered vehicles but a period of rapidly evolving engine development, tighter tailpipe regulations and material supply issues present a unique challenge to catalyst developers.This paper presents an initial study outlining the development of spinel mixed metal oxides for application in modern TWC and addresses some specific challenges underlying this application. Lab and flow reactor data in the study showed how the spinel structure has significant potential in various aspects of the TWC with the necessary improvement in thermal stability. Some initial engine data show three-way performance at or near stoichiometric in a PGM and rare earth free spinel coating and a synergy effect when combined with PGM. An example of a simple calibration modification is shown exploiting the improved three-way window in a combined spinel/low PGM coating.