Unmanned Aerial Vehicles (UAV) require simple and reliable engines of high power to weight ratio. Wankel and two stroke engines offer many advantages over four stroke engines. A two stroke engines featuring crank case scavenging, precise oiling, direct injection and jet ignition is analyzed here by using CAD, CFD and CAE tools. Results of simulations of engine performances are shown in details. The CFD analysis is used to study fuel injection, mixing and combustion. The CAE model then returns the engine performances over the full range of loads and speeds with the combustion parameters given as an input. The use of asymmetric rather than symmetric port timing and supercharging scavenging is finally suggested as the best avenue to further improve power density and fuel conversion efficiency.