Nozzles tip Temperature (NTT) of an injector is a critical parameter for an engine as far as reliability of engine is concerned. It is required to ensure that the injectors operate under its operational limit because higher operating temperatures would result in enlargement of the nozzle spray tip, resulting in higher through flow, producing more undesirable power. This could result in failure of other components in the engine. In this paper we identify the various parameters that are critical for NTT and thereby predict the NTT by having the known input parameters. Response surface methodology and artificial neural network are used to identify the parameters, estimate the significance of each parameter and predict the NTT. Based on this analysis, even without the use of an instrumented injector NTT can be predicted at various working conditions of the vehicle on different terrains.