Internal combustion engines today are required to achieve even higher efficiency and cleaner exhaust emissions. Currently, research interest is focused on premixed compression ignition (Homogeneous Charge Compression Ignition, HCCI) combustion. However, HCCI engines have no physical means of initiating ignition such as a spark plug or the fuel injection timing and quantity. Therefore, it is difficult to control the ignition timing. In addition, combustion occurs simultaneously at multiple sites in the combustion chamber. As a result, combustion takes place extremely rapidly especially in the high load region. That makes it difficult for the engine to operate stably at high loads. This study focused on the fuel composition as a possible means to solve these problems. The effect of using fuel blends on the HCCI operating region and combustion characteristics was investigated using a single-cylinder test engine.