Multidisciplinary Design Optimization (MDO) has been widely used in the automotive industry to balance overall weight and stringent vehicle attributes, such as safety, NVH, durability, etc. To improve product quality and shorten product development cycle, a comprehensive MDO-based platform for vehicle attribute integration is developed in this paper. Some key issues in the platform development are addressed: Parameter model synchronization, Metamodel predictive capabilities, and Pre/post processing, etc. In addition, a strategy for body design is proposed to achieve weight targets while meeting other vehicle attributes. Lastly, the proposed methodology is demonstrated by a real world example for vehicle body design.