Virtual Road Load Data Acquisition (vRLDA) is to replace traditional Road Load Data Acquisition (RLDA) thus becomes the important method to obtain the load for the fatigue analysis of the vehicle components. Pothole event, which is a typical loadcase among vehicle durability test in the development process, is simulated based on Adams/Car in this paper. Flex-body is adopted in the full vehicle model in order to improve the simulation accuracy. Flexible ring tire model, FTire, is used for the benefit of validity in higher frequency domain. The result shows that simulation result correlated well both in wheel center travel and load of tire and suspension parts. Consequently, it is available to predict the max effective jounce travel and body max load in the early phase of vehicle development thus decrease the potential risk in the later phase and the total research cost. vRLDA is also proven as a reliable and effective method to obtain the load.