The transient thermo-mechanical coupling dynamic model of ventilated disc brake with asymmetrical outer and inner thickness was established by means of Msc-marc software. In the model, pad backplate is simplified as a rigid surface with the same shape of brake lining and is bonded together with brake lining. Control node is associated with the rigid surface and the equivalent force that replaces the pressure is applied on the control nodes, of which the degrees of freedom in radial and rotational directions are constrained. With distribution characteristics of disc temperature field, normal stress field and lateral thermo-elastic deformation and thickness for the evaluation, the impacts of brake pad constraints on brake thermomechanical coupling characteristics were analyzed. The simulation results show that the brake pad back plate is an important structure in brake thermo-mechanical coupling analysis, which can’t be ignored in simulation computing. The brake pad constraints can affect thermo-mechanical coupling characteristics of disc brake directly.