The EPA has issued regulations in the Final Rulemaking for 2017-2025 Light-Duty Vehicle Greenhouse Gas Emission Standards and Corporate Average Fuel Economy Standards (420r12901-3). This document provides credits against the fuel economy regulations for various Air Conditioning technologies. One of these credits is associated with increased use of re-circulation air mode, when the Ambient is over 24°C (75°F.). The authors want to communicate the experiences in their careers that highlighted issues with air quality in the interior of the vehicle cabin. Cabin contamination sources may result in safety and health issues for both younger and older drivers. Alertness concerns may hinder their ability to operate a vehicle safely.