Automotive vehicles equipped with Cardan joints may experience a low frequency vehicle launch shudder vibration (5-30Hz) and a high frequency driveline moan vibration (80-200Hz) under operated angles and speeds. The Cardan joint introduces a 2nd order driveshaft speed variation and a 4th order joint articulation torque (JAT) causing the vehicle shudder and moan NVH issues. Research on the Cardan joint induced low frequency vehicle shudder using MBS method has been attempted. A comprehensive MBS method to predict the Cardan joint induced high frequency driveline moan vibration is yet to be developed. This paper presents a hybrid Multi-Body System (MBS) and FEA approach to predict the Cardan joint induced high frequency driveshaft moan vibration. The CAE method considers the elastically coupled driveshaft bending and engine block vibration due to Cardan joint excitation. Detailed driveshaft, joints, slip mechanism, differential, axle and wheel were modeled using a MBS modeling tool. The FEA engine block model was imported using Craig-Bampton method. The CAE driveshaft bending frequency was verified with the Euler-Bernoulli beam equation and a driveshaft impact testing. CAE order cut vibrations at driveline attachment points were correlated with the Dyno test-rig measurements as well as the vehicle test data under various operating conditions. This developed method was used to optimize the Cardan joint induced driveshaft moan performance at upfront with benefits of reducing hardware testing needs, late issue prevention and allowing a most cost effective design to be explored before the hardware prototype is built.