Automotive vehicle manufactures are implementing electrification technologies in many of their vehicle line ups to improve fuel economy and meet emission standards. As a part of electrification, High Voltage (HV) battery packs are being integrated alongside internal combustion engines. Recent generation HV batteries allow extensive power usage, by allowing greater charge & discharge currents & broader state of charge (SOC) ranges. The heat generated during the charge-discharge cycles has to be managed effectively to maintain battery cell performance as well as battery cell life. This situation requires a cooling system with higher efficiency. In general, HV battery packs are either air cooled using cabin interior air or liquid cooled using powertrain cooling systems. Each cooling system supports battery packs heat rejection using different methods and components. As known, each method has its own advantages and shortcomings. While using HV battery pack as an alternative power source, customer expectations regarding driving comfort with respect to cabin climate, cabin interior noise, driver and passengers' leg room, and interior storage space plays a critical role in sizing and selecting the HV battery cooling system. This paper deliberates the factors influencing the selection of liquid cooling over air cooling for a given hybrid electric vehicle architecture.