Drivers’ physical and physiological state changes with prolonged driving. Long time driving can lead to an increased risk of low back pain and other musculoskeletal disorders, caused by the discomfort of the seats. Static and dynamic are the two main categories must be considered within the seating development. The posture and orientation of the occupant are the important factors on static comfort. Driving posture measurement is essential for the evaluation of a driver workspace and improved seat comfort design. This study evaluated the comfortable driving posture through physiological and ergonomics measurements of an automotive premium driver seat. The physiological evaluation includes electroencephalographic (EEG) for brain waves and subjective measurements on 32 healthy individuals. The Biopac system’s AcqKnowledge program was used as a physiological workstation. JACK simulation was used for the ergonomics evaluation, i.e., the magnitude of the spinal loads about lumbar vertebrae was estimated. Sixteen anthropometric characteristics of the population from Size Korea and Size US were used to model digital human in the JACK simulation software. Both male and female with age ranging from 19-65 years, and size (25th, 50th, and 75th) were considered for ergonomics evaluation. Seat back angle from 90 to 135 in 5-degree step were taken into account for both physiological and ergonomics evaluation. Results that the anthropometric characteristics of American and Korean were significantly different. Also, the results of EEG and subjective questionnaire of the healthy individuals, and results of difference in lumbar spinal loads between the two ethics discussed in this paper.