In 2011, Ford Motor Company introduced the first rear seat inflatable belts in Ford Explorer. Interaction of rear inflatable seat belts with child restraint systems (CRS) when it is used to install a CRS or used in conjunction with belt position booster is an important consideration. A comprehensive series of frontal impact sled tests, using a standardized test method, was conducted to compare the performance of a CRS installed using an inflatable seat belt to the identical CRS installed using a standard lap/shoulder belt. The study included rear facing only CRS, both with and without bases, from several CRS manufacturers in the North American CRS market. CRABI 12 month old or Hybrid III 3 year old anthropomorphic test devices (ATD) were restrained in the CRS. The assessment included comparisons of ATD/CRS responses and kinematics, and CRS structural integrity. Overall occupant responses and kinematics were comparable between the inflatable seat belt and the standard lap/shoulder belt installations. When installed without the base, interaction between the inflatable belt system and the rear facing only CRS was minimal while minor differences were noted in CRS and ATD kinematics when installed with the base. No structural integrity issues were identified in CRS installed using inflatable seat belts.