The tire noise is caused due to the complex interactions between the rotating tire and the road surface at the tire/road interface. It is usually caused due to a combination of individually complex noise generation mechanisms, which can be either structural or air related. The influence of each of these noise generation mechanisms may vary, depending on various conditions such as tire design, road surface and operating conditions. Due to the many variables that affect the many noise generation mechanisms in tires, it is usually a very complex task to isolate and categorize those that are present in the overall tire/road noise spectrum. Various approaches are used to categorize noise generation mechanisms in tires. In this paper, a statistical model is used, under the assumption that the tire noise acoustic pressure at a specific frequency band is related to the vehicle speed, in order to study tire noise at different speeds. Consequently, the variation of the speed coefficients with frequency bands is studied for a tire with two transverse slots cut into it, and an attempt is made here, in order to isolate the different noise generation mechanisms as structural or air-borne. While the statistical model is an attempt to indirectly isolate different noise generation mechanisms, it is validated using experimental studies which directly attempt to isolate air-borne and structure-borne noise using foam. This study, while attempting to establish a trend for the variation of tire noise with tire speed, also serves to reinforce the notion that statistical models can be used to isolate the different tire noise generation mechanisms.