Time to torque (TTT) is a quantity used to measure the engine transient torque response. It is referred as the time duration from a full torque command to the time when 95% of maximum torque is achieved. In this work, we seek to control multiple engine actuators in a collaborative way such that the TTT is minimized. We pose the TTT minimization problem as an optimization problem by parameterizing each engine actuator transient trajectory as a Fourier series, followed by minimizing proper cost function with the optimization of those Fourier coefficients. This optimization problem is in general non-convex with unknown structure. To solve the problem in CAE environment, we construct an optimization framework that integrates high-fidelity GT POWER engine model and engine actuators’ Simulink model into modeFrontier computation platform. We conduct simulation study by using this optimization framework on two different turbocharged engines. It is shown that, compared with baseline setup, modifying exhaust variable cam timing (VCT) and Sparking timing transient traces can significantly reduce TTT. Based on this, a new transient control strategy has been proposed and experiment results demonstrate that the new method can reduce the TTT by 20%.