A novel high-speed electromagnetic actuator for electronic fuel injection system of diesel engine is proposed in this paper. By using permanent magnet and annular flange, the design of novel actuator aims to overcome the inherent drawbacks of the conventional solenoid electromagnetic actuator, such as high power consumption and so on. The finite element model (FEM) of novel actuator is developed. Combined with design of experiments and finite element analysis, the second order polynomial response surface models (RSM) of electromagnetic force of novel actuator are produced by the least square principle. Then the influence mechanisms and interaction effects of key design variables on the electromagnetic characteristics of novel actuator are revealed by RSM. What's more, the multi-objective optimization mathematical model (MOMM) of novel actuator based on RSM is built and solved by Genetic Algorithm (GA), aiming to maximize the net electromagnetic force on the armature and minimize the drive current. The Pareto optimal solution set are obtained and the optimal solution is determined. Finally, the higher performance of novel actuator is demonstrated by dynamic finite element analysis.