A methodology for the development of catalyst models is presented. Also, a methodology of the implementation of such models into a modular simulation tool, which simulates the units in succession, is presented. A case study is presented illustrating how suitable models can be found and used for simulations. Such simulations illustrate the behavior of the individual units and the overall system. It is shown how, by simulating the units in succession, the entire after treatment system can be tested and optimized, because the integration makes it possible to observe the effect of the modules on one another.