The 2020+ CO2 and noxious emission limits will impose drastic technological choices. Even though in 2030 65% of road transportation vehicles will be still powered by an Internal Combustion Engine, a progressive increase of hybrids and battery electric vehicles will be confirmed. In parallel, the use of Low-Carbon Alternative Fuels, such as Natural Gas/Biomethane, will play a fundamental role in accelerating the process of de-carbonisation of the transportation sector supporting the virtuous Circular Economy. Since the nineties FCA invested in Compressed Natural Gas (CNG) powered vehicles becoming Market leader with one of the largest related product portfolios in Europe. A progressive improvement of this technology has been always pursued but, facing the next decades, a further improvement of the current CNG powertrain technology is mandatory to achieve even higher efficiency and remove residual gaps versus conventional fuels. Direct Fuel Injection technology will be a step forward because it can be easily applied on new generation spark ignited engines providing simultaneous benefits in terms of performance and engine efficiency, particularly in combination with variable valve actuation, advanced boosting, high compression ratio and alternative combustion cycles (Miller/Atkinson). The paper shows a comprehensive overview of this technology evolution and focuses on a related large collaborative project named GasOn supported by the EU commission.