The Mounting system of component plays a major role in determining the structural durability, compatibility and synchronization of the systems with respect to each other. The major function of Engine mounts is to isolate the engine from the chassis and to align the power-train system of vehicle according to needs. Here we exclusively deal with the failure case of a Heavy duty commercial vehicle Engine Mounts and its optimization. We do formulate a theoretical calculation for the estimation of engine loads, Center of Gravity (C.G) and characteristics of existing engine mount followed by a failure root cause analysis based on design and transmissibility parameters. This is then correlated with data from Computed Aided Engineering and Matlab for analysis of the existing model which is compared to the experimental transmissibility from Road load data Acquisition (RLDA). This is to validate the conditions and propose optimizations to reduce critical failures.