Total vehicle integration and design is a complex process and deals with interactions of many subsystems. The subsystems in a vehicle not only have to perform their role but interfaces between the subsystems must be well understood to design for all the interactions. Global automotive market is following autonomy and electrification trends and vehicle integration design process needs to include those new used cases of autonomous driving and electrification into traditional vehicle design process. The process starts with establishing the top-level vehicle metrics relative to key deliverables of the vehicle ranging from providing comfortable environment to the driver to good performance. The process of establishing vehicle level metrics is not trivial and in lots of cases must be derived from customer verbatim. In lots of cases there are conflicting requirements and priority must be given to one over another. For example, it may not be possible to achieve acceleration performance and fuel economy targets while meeting cost targets. The paper then discusses how the traditional metrics and vehicle design philosophy will evolve with Vehicle Electrification, Active Safety and Autonomy. The paper provides what are the design possibilities as the vehicle evolves to autonomy and electrification and discussed potential solutions.