The spray collapse phenomenon under both flash boiling and non-flash boiling conditions has been intensively reported in recent experimental studies. However, the mechanism of the spray collapse, as well as whether it will have a positive effect on the spray atomization and mixture formation process in the GDI (gasoline direct injection) engine, is still unclear and needs further investigation. In this study, the spray collapse of a multi-hole GDI spray under different fuel temperatures were numerically investigated; so as to provide theoretical support in explaining the mechanism, optimizing the spray atomization and mixture formation processes, and further reducing the PM (particulate matter) emissions of GDI engines. A three-dimensional spray model was established in the CFD (computational fluid dynamics) code ‘Converge’ and was calibrated with high-speed imaging and PDPA (phase Doppler particle analyzer) experiment data. The numerical result showed that the spray collapse under a high fuel temperature condition is mainly attributed to the pressure drop between the inner and outer zone of the spray, which will push the droplets inwards and result in a change of the spray’s trajectory. In addition, increasing the fuel temperature will decrease spray penetration, reduce the incidence of spray impingement and wall wetting phenomenon, and accelerate the spray atomization and mixture formation process in GDI engines.