High performance requirement for the thermal systems in engineering applications have led researchers to search for enhancement techniques that will increase heat transfer rates in a system. Longitudinal vortex generation is a common technique for enhancing heat transfer performance. It can be achieved by employing small flow manipulators, known as vortex generators (VGs), which are placed on the heat transfer surface. The vortex generators can generate longitudinal vortices, which strongly disturb the flow structure, and have a significant influence on the velocity and temperature distributions. The main aim of this study is to conduct a Computational Fluid Dynamics (CFD) analysis, in order to better understand the flow structure and heat transfer mechanisms by longitudinal vortex generation. The simulation will be performed using ANSYS Fluent, and results will be compared to experimental data previously collected from air flow tests through a horizontal channel. Three types of vortex generator arrangements will be evaluated in this study. A small single delta winglet pair, a large single delta winglet pair, and two vortex generator pairs deployed in a V-formation array. The VGs will be fitted vertically on the bottom plate, and different flow conditions will be simulated. Flow through a plain channel will be simulated first and following that, flow characteristics induced by different vortex generators will be analyzed. Three different attack angles will be tested (15 degrees, 30 degrees, and 45 degrees) to evaluate the impact. Potential ways of optimizing the heat transfer within the scope of the project will be noted.