Wide Distillation Fuel (WDF), with a distillation range from Initial Boiling Point (IBP) of gasoline to Final Boiling Point (FBP) of diesel, can be easily gained from the blend of market diesel and gasoline. Polyoxymethylene Dimethyl Ethers (PODE), with good volatility and oxygen content of up to 49%, have great potential to improve combusiton and emission characteristics, especially for soot reduction. In this study, WDF from blend of gasoline and diesel were prepared and the blending ratio is 1:1, by volume. Experiments were carried out in a light-duty four-cylinder diesel engine fueled with pure diesel, gasoline and diesel blends (GD50), GD50/PODE blends (GDP30) and the combustion and emission characteristics were measured. Results showed that PM emission of GDP30 was the lowest and that of diesel was the highest among the three fuels. Due to low ignitability of gasoline component, GD50 has lower combustion efficiency and higher Soluble Organic Fraction (SOF) emissions than those of diesel. This problem can be solved by blending PODE with GD50 because of the high cetane number and oxygen content of PODE. Moreover, GDP30 has higher thermal efficiency than that of diesel and GD50.