Development trends in modern Common Rail fuel injection systems show dramatically increasing capabilities in terms of optimization of the fuel injection pattern through a constantly increasing number of injection events per engine cycle as well as through the modulation and shaping of the injection rate. In order to fully exploit the potential of the abovementioned fuel injection pattern optimization, numerical simulation can play a fundamental role by allowing the creation of a kind of a virtual test rig, where the input is the fuel injection rate and the optimization targets are the combustion outputs, such as the burn rate, the pollutant emissions and the combustion noise. Starting from a previously developed 1D-CFD single cylinder engine model, coupled with a 1D-CFD injector model , this paper presents a methodology for optimizing the fuel injection pattern aiming to minimize Brake Specific Fuel Consumption (BSFC) and Combustion Noise (CN) without exceeding the Brake Specific NOx (BSNOx) baseline value. The NSGA-III algorithm was used in GT-SUITE environment for Pareto optimization in the BSFC-CN space, for 3 different engine operating conditions in the low-medium speed and low-medium load range. The proposed approach highlighted that significant improvements in terms of BSFC and CN can be achieved by adopting digitalized close pilot events with respect to the Design of Experiments (DoE) analysis previously presented in , also highlighting relevant computational time savings for the optimization process.  Sapio, F., Piano, A., Millo, F., Pesce, F.C., “Digital Shaping and Optimization of Fuel Injection Pattern for a Common Rail Automotive Diesel Engine through Numerical Simulation,” SAE Technical Paper 2017-24-0025, 2017.