A 3D grid model of engine brake is established for an automobile engine. The dynamic compression release braking process is simulated by using this model. In the process of engine braking, the movement of valve and piston causes changes of the internal flow field of the engine. In this paper, the movement of valve and piston were defined by using the dynamic grid technology, so that the numerical simulation is closer to the actual situation via the updating of grid. Based on the relevant parameters of compression release engine brake (including the opening of the exhaust valve, the engine speed and the exhaust back pressure), the pressure and power of the compression release braking system were simulated under the conditions of multiple operating conditions and experimental verification was carried out. The results showed that the braking works of the compression release engine brake are mainly from the compression stroke and the exhaust stroke. At a certain speed, each compression release valve opening corresponds to an optimal compression release valve advance angle in order to ensure the optimal engine brake performance. Besides, the larger the compression release valve opening, the smaller the corresponding optimal valve advance angle. Using of decompression brake can achieve better braking effect.