‘LifeSat’ provides unique research opportunities and capabilities for plant biologists. It could provide a regular schedule of flight opportunities to test and investigate a number of important questions in Space biology and gravi-morphogenesis. It could provide a long duration Space environment with much lower levels of g perturbation than might otherwise be possible in the Shuttle or on Space Station Freedom. Since it would be unmanned, one would have access to self-contained, hence more reliable, data gathering than would occur in man-operated experiments. Additionally, if polar flights are implemented, ‘LifeSat’ provides an opportunity to study interaction of ug, hypo-g and radiation. A number of research areas are outlined against a background of plant science objectives and some examples of potential mission scenarios are presented.