Vapor Compression Distillation technology has proved its readiness as a spacecraft wastewater processor as evidenced by selection of this technology for the Urine Processor Assembly aboard Space Station Freedom. In conjunction with Boeing Aerospace Company and the National Aeronautics and Space Administration, Life Systems' technical team has made significant advances in both flight hardware design and software operational aspects. The flight hardware design has focused on Orbital Replacement Unit (ORU) design, ORU rack packaging and ORU weight reduction. On orbit operational aspects of software include operating modes, process control loops, fault detection and fault isolation. These improvements are further indication that Vapor Compression Distillation will be the key to providing wastewater regeneration essential for long-term human survival in space.