Membrane technology for all types of separation processes is developing rapidly. Application of this technology in zero-gravity life support areas such as air revitalization and water reclamation presents special challenges not present in other systems. Design of life support systems for applications such as long duration space missions requires minimization of membrane surface areas as well as system weight and volume. In addition, high membrane selectivity in separating very similar components is required in both gas and water systems. This means that membrane materials for most space life support applications must have both extremely high flux rates and extremely selective permeability characteristics. Programs directed toward developing new materials specifically for space life support systems will be discussed. Specific applications for these new membranes including use of volatile rejection membranes(VRMs) for water reclamation will be given.