The federal emission standards for heavy duty vehicle engines require the exhaust emissions to be measured and calculated in unit form as grams per break horse-power-hour (g/bhp-hr). Correct emission results not only depend on the precise emission measurement but also rely on the correct determination of vehicle energy consumption. A Transportable Heavy-Duty Vehicle Emission Testing Laboratory (THDVETL) designed and constructed at West Virginia University provides accurate vehicle emissions measurements in grams over a test cycle. This paper contributes a method for measuring the energy consumption (bhp-hr) over the test cycle by a chassis dynamometer. Comparisons of analytical and experimental results show that an acceptable agreement is reached and that the THDVETL provides accurate responses as the vehicle is operated under transient loads and speeds. This testing laboratory will have particular value in comparing the behavior of vehicles operating on alternative fuels.