This paper presents the results concerning infrasound pressure levels investigated experimentally in commercial vehicles under differentiated conditions. The investigations come from measurements effected in heavy vehicles operating in specific conditions, as listed below: - function of velocity; - windows and solar roof closed; - solar roof opened; - windows and solar roof partially opened.Under the action of wind attack, the passenger compartment behaves sometimes like a cavity called Helmholtz resonator. The windows and solar roof apertures, and also the volume, are important parameters in this research. The infrasound levels as well the spectrum profiles are analyzed under different conditions, and they are also compared with those obtained with passenger cars. The time exposition is associated to the levels, and some aspects concerning comfort and injury are discussed.