The Russian space program has maintained crews on long duration space flights nearly continuously over the past two decades. As a result, a strong emphasis has been placed on the development of regenerative life support systems. One of these systems is a urine processor which has been operating on-orbit since 1990. The U. S has also been developing urine processing systems to reclaim water from urine over the past twenty years. This paper will describe the two different technologies used for urine processing for long-term human presence in space and will compare the operating characteristics of the two systems.